Symptom recovery and relationship to structure of corpus callosum in individuals with an ‘at risk mental state’

N Katagiri; C Pantelis; T Nemoto; N Tsujino; J Saito; M Hori; T Yamaguchi; T Funatogawa; M Mizuno

Journal article

Symptom recovery and relationship to structure of corpus callosum in individuals with an ‘at risk mental state’

N Katagiri, C Pantelis, T Nemoto, N Tsujino, J Saito, M Hori, T Yamaguchi, T Funatogawa, M Mizuno

Psychiatry Research Neuroimaging | ELSEVIER IRELAND LTD | Published : 2018

DOI: 10.1016/j.pscychresns.2017.11.016

Abstract

Previous studies have revealed that changes in sub-threshold psychotic symptoms observed in individuals with an ‘at risk mental state’ (ARMS) are associated with biological changes in the corpus callosum (CC). To elucidate the biological background for resilience against transition to psychosis, we investigated the relationship between CC structural changes and recovery of sub-threshold psychotic symptom in subjects with ARMS who did not develop psychosis (ARMS-N). Sixteen healthy controls and 42 ARMS (37 ARMS-N) subjects participated this study. The volumes of five sub-regions of the CC were analyzed using MRI. The sub-threshold psychotic symptoms of the ARMS were measured using the Scale o..

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University of Melbourne Researchers

Christos Pantelis Author

Related Projects (1)

RESEARCH FELLOWSHIP - PROF CHRISTOS PANTELIS

I have established and head the Melbourne Neuropsychiatry Centre within the University of Melbourne. My university position is a research ch..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

Naoyuki Katagiri was supported by a JSPS KAKENHI Grant Number 15K19749.Masafumi Mizuno was supported by a Public Grant from the Ministry of Education, Culture, Sports, Science and Technology (MEXT) KAKENHI Grant Number 21591533.Christos Pantelis was supported by a NHMRC Senior Principal Research Fellowship (628386).